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Fuzzy-FishNET: a highly reproducible protein complex-based approach for feature selection in comparative proteomics
BACKGROUND: The hypergeometric enrichment analysis approach typically fares poorly in feature-selection stability due to its upstream reliance on the t-test to generate differential protein lists before testing for enrichment on a protein complex, subnetwork or gene group. METHODS: Swapping the t-te...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260792/ https://www.ncbi.nlm.nih.gov/pubmed/28117654 http://dx.doi.org/10.1186/s12920-016-0228-z |