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Fuzzy-FishNET: a highly reproducible protein complex-based approach for feature selection in comparative proteomics

BACKGROUND: The hypergeometric enrichment analysis approach typically fares poorly in feature-selection stability due to its upstream reliance on the t-test to generate differential protein lists before testing for enrichment on a protein complex, subnetwork or gene group. METHODS: Swapping the t-te...

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Detalles Bibliográficos
Autor principal: Goh, Wilson Wen Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260792/
https://www.ncbi.nlm.nih.gov/pubmed/28117654
http://dx.doi.org/10.1186/s12920-016-0228-z