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Deacetylisovaltratum disrupts microtubule dynamics and causes G(2)/M-phase arrest in human gastric cancer cells in vitro

AIM: Deacetylisovaltratum (DI) is isolated from the traditional Chinese herbal medicine Patrinia heterophylla Bunge, which exhibits anti-cancer activity. Here, we investigated the effects of DI on human gastric carcinoma cell lines in vitro and elucidated its anti-cancer mechanisms. METHODS: Human g...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Zhang, Bo, Zhou, Li-xin, Zhao, Jun, Yan, You-you, Li, Yang-ling, Zeng, Jian-mei, Wang, Lin-ling, Yang, Bo, Lin, Neng-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260834/
https://www.ncbi.nlm.nih.gov/pubmed/27665846
http://dx.doi.org/10.1038/aps.2016.91