Pilot phenotype and natural history study of hereditary neuropathies caused by mutations in the HSPB1 gene

Mutations in HSPB1 are one of the commonest causes of distal Hereditary Motor Neuropathy (dHMN). Transgenic mouse models of the disease have identified HDAC6 inhibitors as promising treatments for the condition paving the way for human trials. A detailed phenotype and natural history study of HSPB1...

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Detalles Bibliográficos
Autores principales: Rossor, Alexander M., Morrow, Jasper M., Polke, James M., Murphy, Sinead M., Houlden, Henry, Laura, Matilde, Manji, Hadi, Blake, Julian, Reilly, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260843/
https://www.ncbi.nlm.nih.gov/pubmed/27816334
http://dx.doi.org/10.1016/j.nmd.2016.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260843/
https://www.ncbi.nlm.nih.gov/pubmed/27816334
http://dx.doi.org/10.1016/j.nmd.2016.10.001

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