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The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling
Among all tissues and organs, the mammary gland is unique because most of its development occurs in adulthood. Notch signaling has a major role in mammary gland development and has been implicated in breast cancer. The vacuolar-ATPase (V-ATPase) is a proton pump responsible for the regulation and co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260869/ https://www.ncbi.nlm.nih.gov/pubmed/27809299 http://dx.doi.org/10.1038/cddis.2016.347 |