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Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress

CD44, a large family of transmembrane glycoproteins, plays decisive roles in physiological and pathological conditions. CD44 isoforms are involved in several signaling pathways essential for life such as growth factor-induced signaling by EGF, HGF or VEGF. CD44 is also the main hyaluronan (HA) recep...

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Detalles Bibliográficos
Autores principales: Shatirishvili, M, Burk, A S, Franz, C M, Pace, G, Kastilan, T, Breuhahn, K, Hinterseer, E, Dierich, A, Bakiri, L, Wagner, E F, Ponta, H, Hartmann, T N, Tanaka, M, Orian-Rousseau, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260879/
https://www.ncbi.nlm.nih.gov/pubmed/27831556
http://dx.doi.org/10.1038/cddis.2016.342