SUMO-specific protease 1 protects neurons from apoptotic death during transient brain ischemia/reperfusion

SUMO-specific protease 1 (SENP1) deconjugates SUMO from modified proteins. Although post-ischemic activation of SUMO conjugation was suggested to be neuroprotective against ischemia/reperfusion (I/R) injury, the function of SENP1 in this process remained unclear. Here we show that transient middle c...

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Detalles Bibliográficos
Autores principales: Zhang, Huijun, Wang, Yan, Zhu, Aoxue, Huang, Dehua, Deng, Shining, Cheng, Jinke, Zhu, Michael X, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260881/
https://www.ncbi.nlm.nih.gov/pubmed/27882949
http://dx.doi.org/10.1038/cddis.2016.290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260881/
https://www.ncbi.nlm.nih.gov/pubmed/27882949
http://dx.doi.org/10.1038/cddis.2016.290

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