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RIPK1 protects from TNF-α-mediated liver damage during hepatitis

Cell death of hepatocytes is a prominent characteristic in the pathogenesis of liver disease, while hepatolysis is a starting point of inflammation in hepatitis and loss of hepatic function. However, the precise molecular mechanisms of hepatocyte cell death, the role of the cytokines of hepatic micr...

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Detalles Bibliográficos
Autores principales: Filliol, Aveline, Piquet-Pellorce, Claire, Le Seyec, Jacques, Farooq, Muhammad, Genet, Valentine, Lucas-Clerc, Catherine, Bertin, John, Gough, Peter J, Dimanche-Boitrel, Marie-Thérèse, Vandenabeele, Peter, Bertrand, Mathieu JM, Samson, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260888/
https://www.ncbi.nlm.nih.gov/pubmed/27831558
http://dx.doi.org/10.1038/cddis.2016.362