Chronic activation of the D156A point mutant of Channelrhodopsin-2 signals apoptotic cell death: the good and the bad

Channelrhodopsin-2 (ChR2) has become a celebrated research tool and is considered a promising potential therapeutic for neurological disorders. While making its way into the clinic, concerns about the safety of chronic ChR2 activation have emerged; in particular as the high-intensity blue light illu...

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Detalles Bibliográficos
Autores principales: Perny, Michael, Muri, Lukas, Dawson, Heather, Kleinlogel, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260891/
https://www.ncbi.nlm.nih.gov/pubmed/27809305
http://dx.doi.org/10.1038/cddis.2016.351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260891/
https://www.ncbi.nlm.nih.gov/pubmed/27809305
http://dx.doi.org/10.1038/cddis.2016.351

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