Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3

Chemoresistance is a major obstacle to effective breast cancer chemotherapy. However, the underlying molecular mechanisms remain unclear. In this study, nuclear receptor coactivator 3 (NCOA3) was found to be significantly increased in taxol-resistant breast cancer tissues and cells. Moreover, overex...

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Detalles Bibliográficos
Autores principales: Ao, Xiang, Nie, Peipei, Wu, Baoyan, Xu, Wei, Zhang, Tao, Wang, Songmao, Chang, Haocai, Zou, Zhengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260895/
https://www.ncbi.nlm.nih.gov/pubmed/27831559
http://dx.doi.org/10.1038/cddis.2016.367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260895/
https://www.ncbi.nlm.nih.gov/pubmed/27831559
http://dx.doi.org/10.1038/cddis.2016.367

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