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TGF-β signaling controls FSHR signaling-reduced ovarian granulosa cell apoptosis through the SMAD4/miR-143 axis

Follicle-stimulating hormone receptor (FSHR) and its intracellular signaling control mammalian follicular development and female infertility. Our previous study showed that FSHR is downregulated during follicular atresia of porcine ovaries. However, its role and regulation in follicular atresia rema...

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Detalles Bibliográficos
Autores principales: Du, Xing, Zhang, Lifan, Li, Xinyu, Pan, Zengxiang, Liu, Honglin, Li, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260897/
https://www.ncbi.nlm.nih.gov/pubmed/27882941
http://dx.doi.org/10.1038/cddis.2016.379