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Inhibition of autophagy increased AGE/ROS-mediated apoptosis in mesangial cells

The aim of our study was to investigate the role of autophagy, a homeostatic process involved in the lysosomal degradation of damaged cell organelles and proteins, in regulating the survival of mesangial cells treated with advanced glycation end products (AGEs). In the present study, AGEs induced mi...

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Detalles Bibliográficos
Autores principales: Xu, Li, Fan, Qiuling, Wang, Xu, Zhao, Xue, Wang, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260901/
https://www.ncbi.nlm.nih.gov/pubmed/27809300
http://dx.doi.org/10.1038/cddis.2016.322