A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation

Human CCAR2 has recently emerged as having a pivotal role in the DNA damage response, promoting apoptosis and repair of heterochromatic DNA breaks. However, less is known about the function of CCAR2 in tumor formation and cancer progression. Here, we demonstrate, for the first time, that CCAR2 loss...

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Detalles Bibliográficos
Autores principales: Restelli, Michela, Magni, Martina, Ruscica, Vincenzo, Pinciroli, Patrizia, De Cecco, Loris, Buscemi, Giacomo, Delia, Domenico, Zannini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260903/
https://www.ncbi.nlm.nih.gov/pubmed/27809307
http://dx.doi.org/10.1038/cddis.2016.359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260903/
https://www.ncbi.nlm.nih.gov/pubmed/27809307
http://dx.doi.org/10.1038/cddis.2016.359

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