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A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA

Ribonuclease L (RNase-L) is an endoribonuclease well known for its roles in innate immunity. Recently it has been shown to regulate several cellular functions by modulating the levels of specific mRNAs. In this study, we investigated whether RNase-L may regulate adipocyte functions. We showed that k...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Chiang, Hou-Hsien, Huang, Ying-Shing, Hsu, Chia-Lang, Yang, Po-Jen, Juan, Hsueh-Fen, Yang, Wei-Shiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260905/
https://www.ncbi.nlm.nih.gov/pubmed/27831565
http://dx.doi.org/10.1038/cddis.2016.323