Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Fbxo7 is a clinically relevant F-box protein, associated with both cancer and Parkinson's disease (PD). Additionally, SNPs within FBXO7 are correlated with alterations in red blood cell parameters. Point mutations within FBXO7 map within specific functional domains, including near its F-box dom...

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Detalles Bibliográficos
Autores principales: Teixeira, Felipe Roberti, Randle, Suzanne J., Patel, Shachi P., Mevissen, Tycho E.T., Zenkeviciute, Grasilda, Koide, Tie, Komander, David, Laman, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260939/
https://www.ncbi.nlm.nih.gov/pubmed/27503909
http://dx.doi.org/10.1042/BCJ20160387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260939/
https://www.ncbi.nlm.nih.gov/pubmed/27503909
http://dx.doi.org/10.1042/BCJ20160387

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