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An Ankyrin-repeat ubiquitin binding domain determines TRABID’s specificity for atypical ubiquitin chains

Eight different types of ubiquitin (Ub) linkages are present in eukaryotic cells that regulate diverse biological processes. Proteins that mediate specific assembly and disassembly of atypical Lys6, Lys27, Lys29 and Lys33 linkages are largely unknown. We here reveal how the human Ovarian Tumor (OTU)...

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Detalles Bibliográficos
Autores principales: Licchesi, Julien D.F., Mieszczanek, Juliusz, Mevissen, Tycho E.T., Rutherford, Trevor J., Akutsu, Masato, Virdee, Satpal, Oualid, Farid El, Chin, Jason W., Ovaa, Huib, Bienz, Mariann, Komander, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260945/
https://www.ncbi.nlm.nih.gov/pubmed/22157957
http://dx.doi.org/10.1038/nsmb.2169