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Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE

Intestinal inflammation plays a critical role in the pathogenesis of intestinal failure (IF). The macrophages are essential to maintain the intestinal homeostasis. However, the underlying mechanisms of intestinal macrophages activation remain poorly understood. Since microRNAs (miRNAs) have pivotal...

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Detalles Bibliográficos
Autores principales: Xiao, Yong-Tao, Wang, Jun, Lu, Wei, Cao, Yi, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260981/
https://www.ncbi.nlm.nih.gov/pubmed/27977009
http://dx.doi.org/10.1038/cddis.2016.426