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Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2
Signal transducer and activator of transcription 5 (STAT5) and nucleophosmin (NPM1) are critical regulators of multiple biological and pathological processes. Although a reciprocal regulatory relationship was established between STAT5A and a NPM–ALK fusion protein in T-cell lymphoma, no direct conne...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260985/ https://www.ncbi.nlm.nih.gov/pubmed/28005077 http://dx.doi.org/10.1038/cddis.2016.430 |