Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2

Signal transducer and activator of transcription 5 (STAT5) and nucleophosmin (NPM1) are critical regulators of multiple biological and pathological processes. Although a reciprocal regulatory relationship was established between STAT5A and a NPM–ALK fusion protein in T-cell lymphoma, no direct conne...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Zhuo, Aerts, Joeri L, Vandenplas, Hugo, Wang, Jiance A, Gorbenko, Olena, Chen, Jack P, Giron, Philippe, Heirman, Carlo, Goyvaerts, Cleo, Zacksenhaus, Eldad, Minden, Mark D, Stambolic, Vuk, Breckpot, Karine, De Grève, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260985/
https://www.ncbi.nlm.nih.gov/pubmed/28005077
http://dx.doi.org/10.1038/cddis.2016.430

Ejemplares similares

Ejemplares similares