Cargando…
Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells
The tumour suppressor p53 plays an important role in somatic cell reprogramming. While wild-type p53 reduces reprogramming efficiency, mutant p53 exerts a gain of function activity that leads to increased reprogramming efficiency. Furthermore, induced pluripotent stem cells expressing mutant p53 los...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260988/ https://www.ncbi.nlm.nih.gov/pubmed/28032868 http://dx.doi.org/10.1038/cddis.2016.419 |