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Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection
The amyloid beta (Aβ) pathway is strongly implicated in neurodegenerative conditions such as Alzheimer's disease and more recently, glaucoma. Here, we identify the α2 adrenergic receptor agonists (α2ARA) used to lower intraocular pressure can prevent retinal ganglion cell (RGC) death via the no...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260990/ https://www.ncbi.nlm.nih.gov/pubmed/27929541 http://dx.doi.org/10.1038/cddis.2016.397 |