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1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis

Foxp3(+) regulatory T (T(reg)) cells contribute to the local dysfunctional immune environment in endometriosis, an estrogen-dependent gynecological disease, which affects the function of ectopic endometrial tissue clearance by the immune system. The reason for the high percentage of peritoneal T(reg...

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Detalles Bibliográficos
Autores principales: Wei, Chunyan, Mei, Jie, Tang, Lingli, Liu, Yukai, Li, Dajin, Li, Mingqing, Zhu, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260991/
https://www.ncbi.nlm.nih.gov/pubmed/27906184
http://dx.doi.org/10.1038/cddis.2016.375