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Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesis

The Notch cascade is a fundamental and highly conserved pathway able to control cell-fate. The Notch pathway arises from the interaction of one of the Notch receptors (Notch1–4) with different types of ligands; in particular, the Notch pathway can be activated canonically (through the ligands Jagged...

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Detalles Bibliográficos
Autores principales: Fazio, Chiara, Ricciardiello, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260996/
https://www.ncbi.nlm.nih.gov/pubmed/27929540
http://dx.doi.org/10.1038/cddis.2016.408