Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis

Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the IκB family, serves as a critical regulator in TGFβ signaling to modulate breast cancer pu...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Cao, Xinwei, Sun, Xiaohua, Lei, Rong, Chen, Pengfei, Zhao, Yongxu, Jiang, Yuhang, Yin, Jie, Chen, Ran, Ye, Deji, Wang, Qi, Liu, Zhanjie, Liu, Sanhong, Cheng, Chunyan, Mao, Jie, Hou, Yingyong, Wang, Mingliang, Siebenlist, Ulrich, Eugene Chin, Y, Wang, Ying, Cao, Liu, Hu, Guohong, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261001/
https://www.ncbi.nlm.nih.gov/pubmed/27906182
http://dx.doi.org/10.1038/cddis.2016.405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261001/
https://www.ncbi.nlm.nih.gov/pubmed/27906182
http://dx.doi.org/10.1038/cddis.2016.405

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