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Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis
Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the IκB family, serves as a critical regulator in TGFβ signaling to modulate breast cancer pu...
Autores principales: | Chen, Xi, Cao, Xinwei, Sun, Xiaohua, Lei, Rong, Chen, Pengfei, Zhao, Yongxu, Jiang, Yuhang, Yin, Jie, Chen, Ran, Ye, Deji, Wang, Qi, Liu, Zhanjie, Liu, Sanhong, Cheng, Chunyan, Mao, Jie, Hou, Yingyong, Wang, Mingliang, Siebenlist, Ulrich, Eugene Chin, Y, Wang, Ying, Cao, Liu, Hu, Guohong, Zhang, Xiaoren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261001/ https://www.ncbi.nlm.nih.gov/pubmed/27906182 http://dx.doi.org/10.1038/cddis.2016.405 |
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