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Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis

Macrophages engulf and destroy pathogens (phagocytosis) and apoptotic cells (efferocytosis), and can subsequently initiate adaptive immune responses by presenting antigens derived from engulfed materials. Both phagocytosis and efferocytosis share a common degradative pathway in which the target is e...

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Detalles Bibliográficos
Autores principales: Yin, Charles, Kim, Yohan, Argintaru, Dean, Heit, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261003/
https://www.ncbi.nlm.nih.gov/pubmed/28005073
http://dx.doi.org/10.1038/cddis.2016.431