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Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases

Although both incidence and aggressiveness of ovarian malignancy rise with age, the exact reason for this tendency, in particular the contribution of senescent cells, remains elusive. In this project we found that the patient's age determines the frequency of intraperitoneal metastases of ovari...

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Detalles Bibliográficos
Autores principales: Mikuła-Pietrasik, Justyna, Uruski, Paweł, Sosińska, Patrycja, Maksin, Konstantin, Piotrowska-Kempisty, Hanna, Kucińska, Małgorzata, Murias, Marek, Szubert, Sebastian, Woźniak, Aldona, Szpurek, Dariusz, Sajdak, Stefan, Piwocka, Katarzyna, Tykarski, Andrzej, Książek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261005/
https://www.ncbi.nlm.nih.gov/pubmed/28032864
http://dx.doi.org/10.1038/cddis.2016.417