Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

In inflammation, extensive cell death may occur, which results in the release of chromatin components into the extracellular environment. Individually, the purified chromatin components double stranded (ds)DNA and histones have been demonstrated, both in vitro and in vivo, to display various immunos...

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Detalles Bibliográficos
Autores principales: Marsman, Gerben, Zeerleder, Sacha, Luken, Brenda M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261016/
https://www.ncbi.nlm.nih.gov/pubmed/27929534
http://dx.doi.org/10.1038/cddis.2016.410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261016/
https://www.ncbi.nlm.nih.gov/pubmed/27929534
http://dx.doi.org/10.1038/cddis.2016.410

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