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Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation
In inflammation, extensive cell death may occur, which results in the release of chromatin components into the extracellular environment. Individually, the purified chromatin components double stranded (ds)DNA and histones have been demonstrated, both in vitro and in vivo, to display various immunos...
Autores principales: | Marsman, Gerben, Zeerleder, Sacha, Luken, Brenda M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261016/ https://www.ncbi.nlm.nih.gov/pubmed/27929534 http://dx.doi.org/10.1038/cddis.2016.410 |
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