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Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2

The epithelial–mesenchymal transition (EMT) is one of the crucial procedures for cancer invasion and distal metastasis. Despite undergoing intensive studies, the mechanisms underlying EMT remain to be completely elucidated. Here, we identified that apoptosis-stimulating protein of p53-2 (ASPP2) is a...

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Detalles Bibliográficos
Autores principales: Wang, Xingwen, Yu, Miao, Zhao, Kunming, He, Mengmeng, Ge, Wenjie, Sun, Yuhui, Wang, Yihua, Sun, Haizhu, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261019/
https://www.ncbi.nlm.nih.gov/pubmed/27929537
http://dx.doi.org/10.1038/cddis.2016.412