Large-scale pharmacological profiling of 3D tumor models of cancer cells

The discovery of chemotherapeutic agents for the treatment of cancer commonly uses cell proliferation assays in which cells grow as two-dimensional (2D) monolayers. Compounds identified using 2D monolayer assays often fail to advance during clinical development, most likely because these assays do n...

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Detalles Bibliográficos
Autores principales: Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261027/
https://www.ncbi.nlm.nih.gov/pubmed/27906188
http://dx.doi.org/10.1038/cddis.2016.360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261027/
https://www.ncbi.nlm.nih.gov/pubmed/27906188
http://dx.doi.org/10.1038/cddis.2016.360

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