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Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

BACKGROUND: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BM...

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Detalles Bibliográficos
Autores principales: Richmond, Rebecca C., Timpson, Nicholas J., Felix, Janine F., Palmer, Tom, Gaillard, Romy, McMahon, George, Davey Smith, George, Jaddoe, Vincent W., Lawlor, Debbie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261553/
https://www.ncbi.nlm.nih.gov/pubmed/28118352
http://dx.doi.org/10.1371/journal.pmed.1002221