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Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones

Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of clonally derived mature CD5(high) B cells; however, the cellular origin of CLL is still unknown. Patients with CLL also harbor variable numbers of CD5(low) B cells, but the clonal relationship of these cells to the bulk disea...

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Detalles Bibliográficos
Autores principales: Bashford-Rogers, Rachael J.M., Palser, Anne L., Hodkinson, Clare, Baxter, Joanna, Follows, George A., Vassiliou, George S., Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261558/
https://www.ncbi.nlm.nih.gov/pubmed/27693386
http://dx.doi.org/10.1016/j.exphem.2016.09.010