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Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of clonally derived mature CD5(high) B cells; however, the cellular origin of CLL is still unknown. Patients with CLL also harbor variable numbers of CD5(low) B cells, but the clonal relationship of these cells to the bulk disea...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261558/ https://www.ncbi.nlm.nih.gov/pubmed/27693386 http://dx.doi.org/10.1016/j.exphem.2016.09.010 |