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Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial

AIM: The combination of weight excess and hypertension significantly contributes to cardiovascular risk and progressive kidney damage. An unfavorable renal hemodynamic profile is thought to contribute to this increased risk and may be ameliorated by direct renin inhibition (DRI). The aim of this tri...

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Detalles Bibliográficos
Autores principales: Kwakernaak, A. J., Roksnoer, L. C., Lambers Heerspink, H. J., van den Berg-Garrelds, I., Lochorn, G. A., van Embden Andres, J. H., Klijn, M. A., Kobori, H., Danser, A. H. J., Laverman, G. D., Navis, G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261569/
https://www.ncbi.nlm.nih.gov/pubmed/28118402
http://dx.doi.org/10.1371/journal.pone.0169258