Cargando…

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis

Decoy receptor 3 (DcR3) has been recently described as an antiapoptosis and prometastasis factor since it can competitively bind to FasL, TL1A, and LIGHT, and it is highly expressed in many malignant tumors. Downregulation of DcR3 can promote tumor cell apoptosis and inhibit metastasis. A previous s...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Chaojie, Xu, Yingchen, Li, Guangming, Zhao, Tuanjie, Xia, Feng, Li, Guanqun, Zhang, Dongxin, Wu, Jixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261847/
https://www.ncbi.nlm.nih.gov/pubmed/28176915
http://dx.doi.org/10.2147/OTT.S127202