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Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis
Decoy receptor 3 (DcR3) has been recently described as an antiapoptosis and prometastasis factor since it can competitively bind to FasL, TL1A, and LIGHT, and it is highly expressed in many malignant tumors. Downregulation of DcR3 can promote tumor cell apoptosis and inhibit metastasis. A previous s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261847/ https://www.ncbi.nlm.nih.gov/pubmed/28176915 http://dx.doi.org/10.2147/OTT.S127202 |