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Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?

To examine the relationship between mitochondrial DNA (mtDNA) alterations and colorectal tumorigenesis, we used high-resolution restriction endonucleases and sequencing to assess the mitochondrial genome from three histologic subtypes of colorectal adenomas (tubular = 8; tubulovillous = 9; and villo...

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Detalles Bibliográficos
Autores principales: Aikhionbare, Felix O, Khan, Masood, Carey, Delicia, Okoli, Joel, Go, Rodney
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526214/
https://www.ncbi.nlm.nih.gov/pubmed/15482594
http://dx.doi.org/10.1186/1476-4598-3-30