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Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?
To examine the relationship between mitochondrial DNA (mtDNA) alterations and colorectal tumorigenesis, we used high-resolution restriction endonucleases and sequencing to assess the mitochondrial genome from three histologic subtypes of colorectal adenomas (tubular = 8; tubulovillous = 9; and villo...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526214/ https://www.ncbi.nlm.nih.gov/pubmed/15482594 http://dx.doi.org/10.1186/1476-4598-3-30 |