The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing

Phosphatidylinositol 4-phosphate 5-kinase (PIP5K), a representative member of the phosphatidylinositol phosphate kinase (PIPK) family, is a major enzyme that biosynthesizes the signaling molecule PI(4,5)P(2) (phosphatidylinositol 4,5-bisphosphate) in eukaryotic cells. The stringent specificity towar...

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Detalles Bibliográficos
Autores principales: Liu, Aizhuo, Sui, Dexin, Wu, Dianqing, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262455/
https://www.ncbi.nlm.nih.gov/pubmed/28138522
http://dx.doi.org/10.1126/sciadv.1600925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262455/
https://www.ncbi.nlm.nih.gov/pubmed/28138522
http://dx.doi.org/10.1126/sciadv.1600925

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