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The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing
Phosphatidylinositol 4-phosphate 5-kinase (PIP5K), a representative member of the phosphatidylinositol phosphate kinase (PIPK) family, is a major enzyme that biosynthesizes the signaling molecule PI(4,5)P(2) (phosphatidylinositol 4,5-bisphosphate) in eukaryotic cells. The stringent specificity towar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262455/ https://www.ncbi.nlm.nih.gov/pubmed/28138522 http://dx.doi.org/10.1126/sciadv.1600925 |