Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers

BACKGROUND: Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs. METHODS: XenoMouse(®)-G2 animals wer...

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Detalles Bibliográficos
Autores principales: Garambois, Véronique, Glaussel, Fabienne, Foulquier, Elodie, Ychou, Marc, Pugnière, Martine, Luo, Robin X, Bezabeh, Binyam, Pèlegrin, André
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526287/
https://www.ncbi.nlm.nih.gov/pubmed/15488142
http://dx.doi.org/10.1186/1471-2407-4-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526287/
https://www.ncbi.nlm.nih.gov/pubmed/15488142
http://dx.doi.org/10.1186/1471-2407-4-75

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