Cargando…
Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers
BACKGROUND: Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs. METHODS: XenoMouse(®)-G2 animals wer...
Autores principales: | Garambois, Véronique, Glaussel, Fabienne, Foulquier, Elodie, Ychou, Marc, Pugnière, Martine, Luo, Robin X, Bezabeh, Binyam, Pèlegrin, André |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526287/ https://www.ncbi.nlm.nih.gov/pubmed/15488142 http://dx.doi.org/10.1186/1471-2407-4-75 |
Ejemplares similares
-
Perspectives on metals-based radioimmunotherapy (RIT): moving forward
por: White, Jordan M., et al.
Publicado: (2021) -
Factors influencing variability of localisation of antibodies to carcinoembryonic antigen (CEA) in patients with colorectal carcinoma--implications for radioimmunotherapy.
por: Boxer, G. M., et al.
Publicado: (1992) -
Involvement of circulating CEA in liver metastases from colorectal cancers re-examined in a new experimental model
por: Leconte, A, et al.
Publicado: (1999) -
Epitopes of carcinoembryonic antigen (CEA) defined by monoclonal antibodies.
por: Price, M. R.
Publicado: (1988) -
A Diagnostic Model With IgM Autoantibodies and Carcinoembryonic Antigen for Early Detection of Lung Adenocarcinoma
por: Zhang, Xue, et al.
Publicado: (2022)