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Ketamine decreases sensitivity of male rats to misleading negative feedback in a probabilistic reversal-learning task

RATIONALE: Depression is characterized by an excessive attribution of value to negative feedback. This imbalance in feedback sensitivity can be measured using the probabilistic reversal-learning (PRL) task. This task was initially designed for clinical research, but introduction of its rodent versio...

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Detalles Bibliográficos
Autores principales: Rychlik, Michal, Bollen, Eva, Rygula, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263208/
https://www.ncbi.nlm.nih.gov/pubmed/27933365
http://dx.doi.org/10.1007/s00213-016-4497-1