Cargando…

The Development of Screening Methods to Identify Drugs to Limit ER Stress Using Wild-type and Mutant Serotonin Transporter

The function of the serotonin transporter (SERT) is regulated by its membrane trafficking. Previously, we showed that the C-terminus-deleted mutant of SERT (SERTΔCT) exhibited an aberrant membrane trafficking and subsequent retention at the endoplasmic reticulum (ER). In addition, we found that prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Katarao, Kazusa, Murakawa, Seiya, Asano, Masaya, Usuki, Naoto, Yamamoto, Hikaru, Shirafuji, Toshihiko, Tanaka, Shigeru, Hide, Izumi, Sakai, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263230/
https://www.ncbi.nlm.nih.gov/pubmed/28127108
http://dx.doi.org/10.1267/ahc.16029