Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by self-renewal. However, the precise temporal and spatial dynamics of the microglial population are unknown. We show in mice and humans that the...

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Detalles Bibliográficos
Autores principales: Askew, Katharine, Li, Kaizhen, Olmos-Alonso, Adrian, Garcia-Moreno, Fernando, Liang, Yajie, Richardson, Philippa, Tipton, Tom, Chapman, Mark A., Riecken, Kristoffer, Beccari, Sol, Sierra, Amanda, Molnár, Zoltán, Cragg, Mark S., Garaschuk, Olga, Perry, V. Hugh, Gomez-Nicola, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263237/
https://www.ncbi.nlm.nih.gov/pubmed/28076784
http://dx.doi.org/10.1016/j.celrep.2016.12.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263237/
https://www.ncbi.nlm.nih.gov/pubmed/28076784
http://dx.doi.org/10.1016/j.celrep.2016.12.041

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