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PPE Surface Proteins Are Required for Heme Utilization by Mycobacterium tuberculosis

Iron is essential for replication of Mycobacterium tuberculosis, but iron is efficiently sequestered in the human host during infection. Heme constitutes the largest iron reservoir in the human body and is utilized by many bacterial pathogens as an iron source. While heme acquisition is well studied...

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Detalles Bibliográficos
Autores principales: Mitra, Avishek, Speer, Alexander, Lin, Kan, Ehrt, Sabine, Niederweis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263243/
https://www.ncbi.nlm.nih.gov/pubmed/28119467
http://dx.doi.org/10.1128/mBio.01720-16