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Comparative analysis of Notch1 and Notch2 binding sites in the genome of BxPC3 pancreatic cancer cells

Notch signaling plays a key role in the development of pancreatic cancer. Among the four identified Notch receptors, Notch1 and Notch2 share the highest homology. Notch1 has been reported to be an oncogene but some reports indicate that Notch2, not Notch1, plays a key role in pancreatic carcinogenes...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Zhou, Ping, Lan, Hong, Chen, Jia, Zhang, Yu-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264041/
https://www.ncbi.nlm.nih.gov/pubmed/28123599
http://dx.doi.org/10.7150/jca.16739