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Strong Correlation of Indoleamine 2,3-Dioxygenase 1 Expression with Basal-Like Phenotype and Increased Lymphocytic Infiltration in Triple-Negative Breast Cancer

Indoleamine 2,3-dioxygenase 1 (IDO1) is an immunosuppressive enzyme involved in tumor immune escape. Blockade of the IDO1 pathway is an emerging modality of cancer immunotherapy. Triple-negative breast cancer (TNBC) lacks established therapeutic targets and may be a good candidate for this novel imm...

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Detalles Bibliográficos
Autores principales: Kim, Sewha, Park, Sanghui, Cho, Min Sun, Lim, Woosung, Moon, Byung-In, Sung, Sun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264048/
https://www.ncbi.nlm.nih.gov/pubmed/28123606
http://dx.doi.org/10.7150/jca.17437