Proteins Involved in HER2 Signalling Pathway, Their Relations and Influence on Metastasis-Free Survival in HER2-Positive Breast Cancer Patients Treated with Trastuzumab in Adjuvant Setting

Aim: Resistance to trastuzumab (which is a standard therapy for breast cancer patients with HER2 overexpression) is associated with higher risk of progression or cancer death, and might be related to activation of signalling cascades (PI3K/AKT/mTOR, Ras/Raf/MAPK) and decreased level of their inhibit...

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Detalles Bibliográficos
Autores principales: Adamczyk, Agnieszka, Grela-Wojewoda, Aleksandra, Domagała-Haduch, Małgorzata, Ambicka, Aleksandra, Harazin-Lechowska, Agnieszka, Janecka, Anna, Cedrych, Ida, Majchrzyk, Kaja, Kruczak, Anna, Ryś, Janusz, Niemiec, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264049/
https://www.ncbi.nlm.nih.gov/pubmed/28123607
http://dx.doi.org/10.7150/jca.16239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264049/
https://www.ncbi.nlm.nih.gov/pubmed/28123607
http://dx.doi.org/10.7150/jca.16239

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