Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na(+)/K(+) ATPase Activity in Dendritic Cells

Leucine-rich repeat kinase 2 (Lrrk2) has been implicated in the pathophysiology of Parkinson’s disease. Lrrk2 is expressed in diverse cells including neurons and dendritic cells (DCs). In DCs Lrrk2 was shown to up-regulate Na(+)/Ca(2+)-exchanger activity. The elimination of Ca(2+) by Na(+)/Ca(2+) -e...

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Detalles Bibliográficos
Autores principales: Hosseinzadeh, Zohreh, Singh, Yogesh, Shimshek, Derya R., van der Putten, Herman, Wagner, Carsten A., Lang, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264149/
https://www.ncbi.nlm.nih.gov/pubmed/28120865
http://dx.doi.org/10.1038/srep41117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264149/
https://www.ncbi.nlm.nih.gov/pubmed/28120865
http://dx.doi.org/10.1038/srep41117

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