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Phosphorylated Histone 3 at Serine 10 Identifies Activated Spinal Neurons and Contributes to the Development of Tissue Injury-Associated Pain

Transcriptional changes in superficial spinal dorsal horn neurons (SSDHN) are essential in the development and maintenance of prolonged pain. Epigenetic mechanisms including post-translational modifications in histones are pivotal in regulating transcription. Here, we report that phosphorylation of...

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Detalles Bibliográficos
Autores principales: Torres-Pérez, Jose Vicente, Sántha, Péter, Varga, Angelika, Szucs, Peter, Sousa-Valente, Joao, Gaal, Botond, Sivadó, Miklós, Andreou, Anna P, Beattie, Sara, Nagy, Bence, Matesz, Klara, C. Arthur, J. Simon, Jancsó, Gábor, Nagy, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264160/
https://www.ncbi.nlm.nih.gov/pubmed/28120884
http://dx.doi.org/10.1038/srep41221